Kiani J, Imam SZ. Medicinal importance of grapefruit juice and its interaction with various drugs. Nutr J. Grapefruit-medication interactions: forbidden fruit or avoidable consequences? Antifungal Agents. Your Privacy Rights. To change or withdraw your consent choices for VerywellHealth. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page. These choices will be signaled globally to our partners and will not affect browsing data.
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Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Selected Sources. Learn About Lipitor Atorvastatin. Taking Statins? Put Down the Grapefruit Juice. General Information About Livalo Pitavastatin. As a result, more of the drug is absorbed, making it more powerful than it's meant to be — even toxic in some cases.
Not all statins are affected equally by grapefruit juice, so grapefruit fans might want to switch to a statin that's less affected see the table below. But if you can't switch, experts say it's probably okay to enjoy a small glass. That's because the studies showing dangerous effects used massive amounts of furanocoumarins, the amount found in a quart or more of the juice.
What's more, eating half a grapefruit is even less risky than drinking grapefruit juice, since it takes several fruits to make a single glass of juice.
But to be on the safe side, check with your doctor, and avoid taking your pills with grapefruit juice. As a service to our readers, Harvard Health Publishing provides access to our library of archived content.
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Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight loss They're given to people at high risk of getting clots, to reduce their chances of serious conditions such as strokes and heart attacks. Do not drink grapefruit juice if you're taking warfarin. It can increase the effect of warfarin on your blood, making you bleed more easily. It's safer to drink grapefruit juice if you're taking the newer anticoagulants rivaroxaban , dabigatran , apixaban or edoxaban.
Antiplatelet medicines prevent platelets a type of blood cell from sticking together and forming blood clots. They help to prevent heart attacks and strokes.
Do not drink grapefruit juice if you're taking the antiplatelet medicine clopidogrel , as it may mean your medicine works less effectively. If you're taking ticagrelor , grapefruit may increase the effects of your medicine and make you bleed more easily. You do not need to avoid grapefruit if you're taking dipyridamole or low-dose aspirin.
Ciclosporin, sirolimus and tacrolimus are medicines that moderate your immune system the body's natural defence system. If you're taking any of these medicines, do not drink grapefruit juice without consulting your doctor.
Entocort is a medicine that contains budesonide and is used to treat Crohn's disease , a condition that affects the digestive system. Do not eat grapefruit or drink grapefruit juice while you're taking this medicine, as the level of budesonide in your blood will increase. Some medicines used in the treatment of cancers may interact with grapefruit juice. You should check with your doctor before drinking grapefruit juice.
This list is not exhaustive and there are a number of other drugs that may interact with grapefruit. The risk of experiencing the effect of a drug interaction as a result of grapefruit can vary a lot from person to person.
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